Monday, February 25, 2013

Cancer drugs proving worth earlier in testing

Dr. Michael Weitz, MD, poses in the emergency room at St. John's Health Center in Santa Monica, California, February 13, 2013. Drug makers are finding out much earlier in the testing process whether cancer drugs work and Dr. Weitz, whose lung cancer was quickly eradicated in a Phase 1 trial, is an example of this trend. Picture taken February 13, 2013.  Credit: Reuters/Bret Hartman

NEW YORK | Mon Feb 25, 2013 9:07am EST

(Reuters) - Michael Weitz had options. The Californian had undergone chemotherapy, radiotherapy and surgery, but his lung cancer still spread to his bones and the brain.

With time running out, the doctor of the emergency room is entered a phase I study - the first step in human testing of a new drug - of crizotinib. The drug works for about 4 percent of patients with advanced lung cancer with a mutated form of a protein called ALK.